Affiliation:
1. Nagoya University Graduate School of Medicine
2. Toho University Omori Medical Center
3. Mie University
Abstract
Abstract
Purpose
Gastrointestinal bleeding (GIB) due to esophageal varices (EV) is one of the factors that negatively impacts native liver survival of patients with biliary atresia (BA). Gastrointestinal fibroscopy (GIF) is usually used to determine the presence of EVs; however, it require general anesthesia. The aim of this study is to search for markers in blood tests obtained during routine check-ups that can predict the development of GIB.
Methods
Data of patients with BA who underwent portoenterostomy at our hospital from 2014 to 2020 were retrospectively reviewed. The patients’ data were assigned to three groups according to specific time points: Group B, which included data at GIB; Group NB-T, which included data at GIF and EV treatment; and Group NB-NT, which included data at GIF without treatment. The data in Group B were compared to those of other groups.
Results
In our study, GIB occurred in 11 patients, and 12 cases, and 8 cases were classified into Groups NB-NT and NB-T, respectively. Compared with the other groups, only ChE and M2BPGi in Group B showed statistically significant differences.
Conclusions
ChE and M2BPGi are useful for predicting GIB.
Publisher
Research Square Platform LLC