A Greener Biocatalyst promoted Synthesis of Novel pyridine-based Schiff base: Synthesis of their metal complex; In silico molecular docking and In-vitro biological studies and its Photocatalytic dye degradation

Abstract

Abstract In the present study a series of new Pyridine based schiff bases were synthesized by natural acid that was extracted from certain citrus fruits. By using a metal salt of NiCl2×6H2O, CoCl2×6H2O and Na2PdCl4 to synthesized a metal complexes. Structure of these compounds were confirmed by standard study of MS, LC-MS, FTIR, 1H NMR, 13C NMR, TGA, UV-spectroscopy. Antibacterial activity of synthesized molecules was tested against Gram-positive (S. aureus and E. faecalis) and Gram-negative (E. coli and P. aeruginosa) bacterial strains. Co (II), Ni (II) and Pd (II) metal complexes were used for the photocatalytic degradation of Ramazol brilliant blue R (RBBR) dye with the help of UV visible spectroscopy. The staphyloma concourses microbial structure was pre-processed for docking study using the AutoDock-Vina. The mentioned green chemistry techniques are economical, easy to understand, and give more effective extraction while showing maximum efficiency.