Creating silver nanoparticles through the biogenic synthesis process using marine fungi Aspergillus flavus OQ651270: Examining their characterization and conducting biological studies.

Author:

Al-Agamy Mohamed H.,Kelany Mahmoud S.,Alhuzani Mohammad R.,Hamed Moaz M

Abstract

Abstract Silver nanoparticles (Ag-NPs) have gained widespread attention due to their diverse applications in modern technology, prompting extensive research and development efforts. This study focuses on investigating the antibacterial properties of Ag-NPs, encompassing their production, characterization, and biological aspects. The eco-friendly extracellular biosynthetic method employed in this work utilized extracts from the marine fungus Aspergillus flavus MK4 as reducing agents for nanoparticle synthesis. UV-visible spectroscopy revealed the colloidal Ag-NPs, with a Plasmon absorbance peak observed at 450 nm. Transmission electron microscopy (TEM) elucidated the spherical shape and 15 nm size of the Ag-NPs. Evaluation against both Gram-negative and Gram-positive bacteria demonstrated significant antibacterial activity. Cytotoxicity against the HepG-2 cell line was assessed using the MTT assay, and antioxidant properties were examined through the radical scavenging (DPPH) assay. The synthesized Ag-NPs exhibit promising characteristics for applications in antibacterial, anticancer, and wound-healing contexts. Aspergillus flavus MK4, with its robust Ag-NP synthesis capability, produces well-characterized nanoparticles with proven antibacterial, antioxidant, anticancer, and wound-healing properties.

Publisher

Research Square Platform LLC

Reference59 articles.

1. Fungi in aquatic ecosystems;Grossart H-P;Nature Reviews Microbiology,2019

2. The numbers of fungi: is the descriptive curve flattening?;Hyde KD;Fungal Diversity,2020

3. The Faces of Fungi database: fungal names linked with morphology, phylogeny and human impacts;Jayasiri SC;Fungal diversity,2015

4. Marine fungi: A source of potential anticancer compounds;Deshmukh SK;Frontiers in microbiology,2018

5. Lal HM, Thomas S, Li T, Maria HJ: Polymer Nanocomposites Based on Silver Nanoparticles: Springer; 2021.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3