Central Retinal Vein Occlusion Associated with Bartonella Henselae Infection

Author:

Bellur Sunil1,Ali Amir2,Nguyen Nam V.3,Fernandes Joshua K.4,Kodati Shilpa1

Affiliation:

1. National Eye Institute, National Institutes of Health

2. University of Texas Medical Branch

3. University of Nebraska Medical Center

4. DC Retina

Abstract

Abstract Purpose: To report the clinical features and treatment course of a case of central retinal vein occlusion (CRVO) as the initial sign of ocular Bartonella henselae (B. henselae) infection. Observation: A 36-year-old male was evaluated for unilateral vision loss. He denied prodromal symptoms but reported prior exposure to fleas. Best corrected visual acuity (BCVA) was 20/400 in the left eye. Clinical examination revealed a CRVO with atypical features including significant peripapillary exudates and peripheral vascular sheathing. Laboratory testing revealed elevated B. henselae IgG titers (1:512) with no abnormalities on hypercoagulability testing. The patient was treated with doxycycline and aflibercept with an excellent clinical response and improvement in BCVA to 20/25 in the left eye two months later. Conclusion: CRVO is a rare but sight-threatening complication of ocular bartonellosis and can be the presenting sign of infection, even in the absence of cat exposure or prodromal symptoms.

Publisher

Research Square Platform LLC

Reference17 articles.

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2. Ocular Bartonella Infections;Roe RH;Int Ophthalmol Clin,2008

3. Cat-scratch disease;Chomel BB;Rev Sci Tech Apr,2000

4. Pathogenicity and treatment of Bartonella infections;Angelakis E;Int J Antimicrob Agents Jul,2014

5. Cat-scratch disease;Biancardi AL;Ocul Immunol Inflamm Apr,2014

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