Application of multidisciplinary treatment in the diagnosis and treatment of patients with advanced colorectal cancer：a retrospective study in China

Abstract

Objective Analyze the application and value of multidisciplinary treatment (MDT) for stage IV colorectal cancer patients and summarize work experience. Methods The clinical data of patients with stage IV colorectal cancer from January 2017 to December 2021 in the Department of Colorectal Surgery of the hospital were retrospectively analyzed. Patients who received MDT were included in the MDT group, and patients who did not receive MDT were included in the Non-MDT group. The basic information and follow-up data of the two groups were collected, and the general baseline data (including gender, age, pathological stage, primary tumor location, intestinal obstruction, number of metastatic organs, and location of metastasis) and the one-year, two-year, and three-year survival rates of the two groups were compared by chi-square test. The hospital stay and hospitalization cost of the two groups were compared by Z test. The survival curve was drawn by the Kaplan-Meier method, and the difference in overall survival rate between the two groups was compared by log-rank test. Results A total of 544 patients with stage IV colorectal cancer (staged according to the NCCN guidelines for clinical staging of tumors) were enrolled. There were no statistically significant differences in gender, age, pathological stage, primary tumor location, number of metastatic organs, metastatic sites, and intestinal obstruction between the two groups (P > 0.05). The hospital stay and hospitalization cost of the MDT group were lower than those of the Non-MDT group, and the differences were statistically significant (P < 0.05). The survival curve indicated that the overall survival cycle of the MDT group was longer than that of the Non-MDT group. Conclusions Most patients with advanced colorectal cancer are complicated cases. The multidisciplinary diagnosis and treatment service mode can improve the survival cycle of hospital stay of patients, and improve the operation efficiency of hospitals. implications for Cancer Survivors multidisciplinary treatment care enables cancer survivors to receive proper diagnosis and treatment, increases survival time, improves patients' quality of life, and reduces all costs.