Virulence gene expression of halophilic variant V.parahaemolyticus and its effect on pathogenicity

Author:

Dong Xin1,Wu Dan1,Chen Jia1,Du Qiang1,Tu Bowen1,Mao Xujian1,Wang Fengming1,Zhao Ying1

Affiliation:

1. Changzhou Center for Disease Control and Prevention

Abstract

Abstract

Vibrio parahaemolyticus (VP) is a Gram-negative halophilic bacterium that mainly infects seafood and food [1] with high salt content. Eating uncooked or contaminated by the bacteria may cause gastroenteritis symptoms, such as nausea, vomiting and diarrhea [2]. In many countries, especially in coastal [3], VP has become the leading pathogen [4] responsible for bacterial food poisoning, and foodborne diseases caused by VP have also become a public health issue of global concern. We show that halinophilia is one of the most unique biological properties of VP, [5], which can only normally grow [6] in environments with 0.5–8.0% salt content. In recent years, an increasing number of literature has reported that the prevalence of VP in inland cities gradually increases in [7–9]. The VP monitoring results of ready-to-eat raw aquatic products in Changzhou found that the detection rate of VP was increasing year by year, especially the proportion of VP detected in freshwater products increased significantly, and VP was detected in freshwater crayfish, freshwater fish and shellfish. The preliminary research results of this project team found that VP of fresh water products could grow normally at 0%~0.5% salt concentration, while VP of seawater products grew well at salt concentration of 1%~3%, which proved that the halinophilia of some VP was changed, and the "halophilic variant" VP appeared.

Publisher

Springer Science and Business Media LLC

Reference25 articles.

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2. Craig Baker-Austin, Oliver JD, Alam M et al (2018) Vibrio spp infections Nat Rev Dis Primers 4(1):8

3. Paulinus Chigbu, et al.Antimicrobial and Genetic Profiles of Vibrio vulnificus and Vibrio parahaemolyticus Isolated From the Maryland Coastal Bays, United States;Ligia Vda;Front Microbiol,2021

4. Copin MB-JCédric, Le Bris et al (2019) Vibrio species involved in seafood-borne outbreaks (Vibrio cholerae, V.parahaemolyticus and V.vulnificus): Review of microbiological versus recent molecular detection methods in seafood products.Crit Rev Food Sci Nutr.;59(4):597–610

5. Dan Gu, et al.Molecular mechanisms of Vibrio parahaemolyticus pathogenesis;Li L;Microbiol Res,2019

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