Tracing the Ancestral Footprints: Unraveling Thailand's Mitochondrial Heritage through Comprehensive Analysis of Expanded mtDNA Data

Author:

Jaisamut Kitipong1,Pitiwararom Rachtipan1,Sukawutthiya Poonyapat1,Sathirapatya Tikumphorn1,Noh Hasnee1,Worrapitirungsi Wikanda1,Vongpaisarnsin Kornkiat1

Affiliation:

1. Chulalongkorn University

Abstract

Abstract The evolutionary dynamics of mitochondrial DNA (mtDNA) within the Thai population were comprehensively explored with a specific focus on the influence of South Asian admixture. A total of 166 samples were collected through randomized sampling, ensuring a diverse representation. Our findings unveil substantial genetic and haplogroup diversity within the Thai population. We have identified 164 haplotypes categorized into 97 haplogroups, with a notable inclusion of 20 novel haplogroups. The distribution of haplogroups exhibited variations across different populations and countries. The central Thai population displayed a high diversity of haplogroups from both the M and N clades. Maternal lineage affinities were discerned between several Mainland Southeast Asia (MSEA) and South Asian populations, implying ancestral genetic connections and a substantial influence of South Asian women in establishing these relationships. f4-statistics indicates the presence of a Tibeto-Burman genetic component within the Mon population from Thailand. New findings demonstrate two phases of population expansion occurring 22,000–26,000 and 2,500-3,800 years ago, coinciding with the Last Glacial Maximum, and Neolithic demographic transition, respectively. This research significantly enhances our understanding of the genetic history of Thailand and MSEA, emphasizing the influence of South Asian admixture. Moreover, it underscores the critical role of prior information, such as mutation rates, within the Bayesian framework for accurate estimation of coalescence times and inferring demographic history.

Publisher

Research Square Platform LLC

Reference75 articles.

1. Higham, C. Early Mainland Southeast Asia. From first humans to Angkor. Antiquity (River Books Press Dist A C, 2014).

2. When did homo sapiens first reach Southeast Asia and Sahul?;O’Connell JF;Proc Natl Acad Sci U S A,2018

3. Early presence of Homo sapiens in Southeast Asia by 86–68 kyr at Tam Pà Ling, Northern Laos;Freidline SE;Nat. Commun,2023

4. Homo Sapiens Societies in Indonesia and South-Eastern Asia;O’Connor S,2014

5. The Hoabinhian: The Late and Post-Pleistocene Cultural Systems of Southeast Asia;Shoocongdej R;The Oxford Handbook of Early Southeast Asia,2022

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3