Affiliation:
1. Tehran University of Medical Sciences
2. Tehran University of Medical Science
Abstract
Abstract
Objective: Neonatal mortality remains a global public concern. The aims of the study were the evaluation of survival in all admitted infants in the NICU, as well as overall and periodic predictors of neonatal mortality from 2016 to 2022.
Methods: A retrospective cohort study was conducted among a total of 7255 neonates who were admitted to the NICU in Valiasr Hospital (in the capital of Iran).
Result: Mortality in preterm neonates was 9.1%, this percentage was 6.6% in all neonates. Mortality proportion had been declining from the majority of medical morbidities from 2016 to 2022. The most visible decline was observed for respiratory disorders, prematurity, and sepsis. In the adjusted Cox regression, gestational age, birth weight, one and fifth-minute APGAR scores, congenital defects (HR=2.02), sepsis (HR=1.63) respiratory disorders (HR=1.40), intervention treatments, and antibiotic administration history were continued as predictor variable of death.
Conclusion: Although the probability of survival seems to be increasing over the past years in Iran, it is far away from the target for 2030. The most common causes of neonatal mortality were congenital defects, sepsis, and respiratory disorders.
Publisher
Research Square Platform LLC