Predictive Value of Haemoglobin to Creatinine Ratio for Contrast Induced Nephropathy

Abstract

Abstract Background Hemoglobin and creatinine levels are important factors for contrast induced nephropathy (CIN) development. Our aim in this study is to investigate the predictive value of Hemoglobin to Creatinine ratio (HCR) for CIN development in patients undergoing investigations using contrast media. Methods A total of 97 patients who underwent contrast requiring radiological investigations were evaluated prospectively in terms of CIN. HCR was calculated as baseline Hemoglobin/baseline serum creatinine value. Glomerular filtration rate (GFR) was calculated with the Cockcroft-Gault formula. All the measured parameters were compared and analysed to calculate the HCR. Results CIN was detected in 6.19% (6 out of 97) patients. In receiver operating characteristics (ROC) analysis; AUC = 0.96 for Hemoglobin to creatinine ratio, p < 0.001, AUC for HB1 = 0.982 p < 0.001. The cutoff value of HCR was ≤ 7.91 and the cutoff value of HB1 was ≤ 8.8 g/dL for the development of CIN. Conclusions Hemoglobin to creatinine (HCR) ratio, HB1 and contrast amount used are significant predictors for CIN development in patients.