Long-term outcomes of physical activity counseling in in-patients with major depressive disorder: Results from the PACINPAT randomized controlled trial
Author:
Kreppke Jan-Niklas1, Cody Robyn, Beck Johannes, Brand Serge, Donath Lars, Eckert Anne, Faude Oliver, Hatzinger Martin2, Imboden Christian3ORCID, Lang Undine1, Ludyga Sebastian1ORCID, Mans Sarah, Mikoteit Thorsten, Oswald Anja, Schweinfurt Nina, Holsboer-Trachsler Edith, Zahner Lukas, Gerber Markus
Affiliation:
1. University of Basel 2. University of Basel Switzerland 3. Private Clinic Wyss, Münchenbuchsee, Switzerland
Abstract
Abstract
Background: Major depressive disorder (MDD) is an increasingly common psychiatric illness associated with a high risk of insufficient physical activity, which in turn is associated with negative mental and physical health outcomes. Theory-based, individually tailored, in-person and remote physical activity counseling has the potential to increase physical activity levels in various populations. Given this, the present study investigated the effect of such a physical activity intervention on the physical activity behavior of in-patients with MDD.
Methods: This was a multi-center, two-arm randomized controlled trial including initially insufficiently physically active adult in-patients with MDD from four study sites in Switzerland. The sample consisted of 220 participants (Mage = 41 ± 12.6 years, 52% women), 113 of whom were randomized to the intervention group and 107 to the control group. The main outcome, moderate-to-vigorous physical activity (MVPA), was assessed at three time points via hip-worn accelerometer.
Results: According to accelerometer measures, there was no significant difference in minutes spent in MVPA over a 12-month intervention period when comparing the intervention with the control group (β = -1.02, 95% CI = -10.68 to 8.64). Higher baseline physical activity significantly predicted physical activity at post and follow-up.
Conclusion: This study showed that it is feasible to deliver an individually tailored, theory-based physical activity counseling intervention to in-patients with MDD, however yielding no significant effects on accelerometer-based MVPA levels. Further efforts are warranted to identify efficacious approaches.
Trial registration: ISRCTN, ISRCTN10469580, registered on 3rd September 2018, https://www.isrctn.com/ISRCTN10469580
Publisher
Research Square Platform LLC
Reference76 articles.
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