Sleep-related painful erections: a survey-based analysis of patient-reported experiences with diagnosis and management

Abstract

Abstract Sleep-related painful erection (SRPE) is a condition characterized by painful nocturnal erections and frequent nighttime awakenings. The pathophysiology of SRPE is not well understood and existing literature consists mainly of case reports. We aimed to investigate the causes, treatments, and impact on quality of life among individuals affected by SRPE. A questionnaire comprising 30 items was administered to a group of men with SRPE. The survey collected information on demographics, clinical and social history, symptomatology, interventions and quality of life. 44 patients with SRPE responded to the survey, with a mean age of 43.3 years. Most respondents had no relevant medical history related to erectile function disorders. 43% of subjects reported sleep apnea, and 27% reported a mental health disorder or psychiatric medication use. Baclofen was the most common medication, but only 25% of patients found it beneficial. Sleep repositioning, oxygen device use and pelvic floor therapy were interventions that provided the most relief. Most patients did not require emergency department visits (93%); only a small number needed penile aspiration (n=2). As reported by most respondents, SRPE significantly impacted patients' quality of life. The findings highlight the need for further research to understand SRPE better and develop effective treatment options.