Association between high birth weight and dental caries at 4-5 years of age: a birth-cohort study

Author:

Zhang Hao1,Wang Huning1,Zeng Xiaoli1,Yu Jin1,Jiang Yiwei1,Huang Lisu2,Zeng Xinxin2,Chen Qian3,Da Dongxin1,Zhang Ying1

Affiliation:

1. Department of Preventive Dentistry, Shanghai Stomatological Hospital & School of Stomatology, Fudan University

2. Department of Pediatrics Infectious Diseases, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

3. MOE-Shanghai Key Laboratory of Children’s Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Abstract

Abstract Objective: Early childhood caries has become a globally crucial oral health problem over the decades. Most studies have discussed the association between low birth weight and early childhood caries; however, studies focusing on high birth weight have been relatively limited. This study aimed to assess the impact of high birth weight on the incidence and severity of dental caries in 4–5-year-old children. Subjects and Methods: Study subjects included 491 children from a birth cohort study at 4–5 years of age. Data on dental caries, prenatal and perinatal factors, and socio-demographic determinants were recorded. Logistic regression models adjusted for potential confounders were performed to analyze the data. Two-sided P-value < 0.05 was considered statistically significant. Results: Of the 491 children, the prevalence of dental caries was 48.7%. High birth weight (≥ 4,000 g) was significantly associated with increased incidence of dental caries (OR, 2.000; CI 95% 1.062–3.765), and the relatively enhanced risk OR was further increased in subjects experiencing caries (dmft ≥ 3) (OR, 2.437; CI 95% 1.306–4.549) compared with the normal birth weight (2,500–3,999 g). Conclusions: High birth weight is a risk factor for early childhood caries. Particular attention should be paid to children with birth weight more than or equal to 4,000 grams.

Publisher

Research Square Platform LLC

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