Health-related quality of life and associations on socio-demographic and clinical factors in schizophrenia based on the QLICD-SC scale: A cross-sectional study

Abstract

Abstract Purpose This paper aimed at providing evidence for developing countermeasures to improve patients’ quality of life by using the scale Quality of Life Instruments for Chronic Diseases-Schizophrenia (V2.0)(QLICD-SC)), which is modular and sensitivity. Methods 163 people who met the diagnostic criteria for schizophrenia of the International Classification of Diseases(10th Revision) and were hospitalized at the Affiliated Hospital of Guangdong Medical University from May 2014 to December, 2015 were selected. Patients' clinical objective indexes, including blood routine, urine routine, blood biochemical examination, blood gas analysis etc. were collected by reviewing the medical records. Patients were assessed by the QLICD-SC (V2.0), a quality of life measurement scale for Schizophrenia. Simple correlation analysis was used to explore the correlation between the QLICD-SC (V2.0) scores and various clinical objective indicators, and multiple linear regression was used to further screen for correlates. Results There were 163 participants, ranging in age from 16 to 69, with a 30.67 ± 11.44 average age. The majority of them were men(57.1%), had a high school diploma(77.9%), and were married (65.6%). According to multiple linear regression, the variables included in the model are education, sex, eosinophilic granulocyte, hematocrit, percentage of monocytes, phosphorus (R2 = 0.065 ~ 0.222, P < 0.05). Conclusion Some clinical indicators such as hematocrit and socio-demographic factors may reflect alterations in the quality of life of individuals with schizophrenia.