Stena Multilayer Flow Modulator in Aortic Aneurysms: An Overview Based on Preclinical Experience

Abstract

Abstract Background: Aortic aneurysm (AA) is still an important public health problem worldwide. Endovascular aneurysm repair (EVAR) is currently primary treatment option because of the side effects of surgery. Significant efforts are being made to reduce the AA-associated adverse events. In this article, the multilayer flow modulator approach is discussed based on the results of patients treated with Stena Multilayer Flow ModulatorⓇ (S-MFM) (Invamed, Ankara) by reviewing literatures published on the subject. Material Methods: It was evaluated 6-month follow-up outcomes of 12 patients (nine men and three females; mean age 60 years, range 34-79 years) underwent aneurysm repair with the S-MFM between July 2022 and December 2022. Results: The control angiograms confirmed successful patency in the lumen of the main aorta and the branches in all cases. The technical success was 100%, and no case required immediate intervention. Significant complications such as ruptures, stent migrations, retractions, thrombosis, fractures were not observed. No endoleak associated with the at the proximal and distal ends was observed. Conclusions The current data show the multilayer flow modulator approach may be an attractive alternative to surgery or EVAR for aortic aneurysm. While it shrinks the aneurysm sac and protects the side branch blood flow, it reduces the risks of mortality and morbidity. It can be easily applied in complex aortic aneurysms and its ready-to-use structure that does not require personalized production shortens the waiting time for intervention. Further research and longer follow-up are needed.