Prospetive evaluation of the risk of compartmental intra-abdominal pressure on mortality in severe acute pancreatitis

Abstract

Abstract Background Death in the hospital is significant in patients with severe acute pancreatitis (SAP). They have elevated intraabdominal pressure (IAP), which might result in organ dysfunction. The study's goals were to look at the overall incidence of rising IAP in SAP patients as well as the progression of organ dysfunction and risk mortality factors for higher IAP. Methods Between 2020 and 2023, 118 cases of acute pancreatitis were managed in Zagazig University Hospital's intensive care unit (ICU). Patients were categorised into quartiles 1–4. The intravesical technique was used to assess elevated IAP. Results Peak IAP, max SOFA score, max APACHE II score, top creatinine, and age, with lactate peak level, were substantially related to IAP and higher in nonsurvivors. The maximal IAP in retrospective groups 1–4 was 7–14, 15–18, 19–24, and 25–33 mmHg, correspondingly, with hospital mortality rates of 10%, 12.5%, 22.2%, and 50%. Respectively, with significant statistics. The highest quality of ICU-free days was 45.7, 38.8, 32.0, and 27.5 days, respectively. Categories one to four have significant statistics. Conclusion Greater IAP in SAP cases presented with early organ damage and fewer ICU-free days. IAP is assessed throughout ICU inpatient care to prove the cure rate after decompression.