Factors Associated with Completion and Improvement Following Integrative Oncology Acutherapy in a Racially-Diverse Population

Author:

Zelaya María Grosso1,Nicaise Edouard H.1,Hartsoe Blaise1,Melikian Margarite2,Catic Almira1,Patil Dattatraya1,Ben-Arye Eran3,Bausum Anna2,Master Viraj A.1

Affiliation:

1. Emory University School of Medicine

2. Emory University

3. Clalit Health Services

Abstract

Abstract

Background Acutherapy is an important integrative therapy in oncology settings as an adjunctive management option for cancer-related adverse effects. However, barriers to utilization of acupuncture in minority populations have been reported. This study sought to assess factors that impact completion of a recommended acutherapy regimen in a racially diverse cohort of cancer patients, along with determining the usefulness of functioning and well-being questionnaires in evaluating acupuncture outcomes. Methods We prospectively enrolled 432 patients who completed at least one acutherapy visit from the Integrative Oncology Program at the Winship Cancer Institute. Demographic characteristics were collected. PROMIS-29 questionnaire was administered at baseline and follow-up to measure patient-reported outcomes across domains of functioning and well-being. Logistic regression models were created to examine factors associated with regimen completion among all patients, and domain improvement among patients with reported symptoms following regimen completion. Results There were 432 patients included: 153 (35.1%) attended 8 or more sessions. Multivariable logistic regression showed that non-white race (OR 0.63; p = 0.047) and active treatment status (OR 0.54; p = 0.005) were associated with decreased adherence to the recommended acutherapy regimen. No differences in rate of posttreatment improvement were observed across race or cancer status. Non-white patients had greater moderate/severe scores in the domains of physical functioning (baseline: 54.2% vs. 32.4%; p = 0.019 | posttreatment: 50.0% vs. 18.1%; p < .001) and pain interference (baseline: 34.3% vs. 62.5%; p = 0.005 | posttreatment: 60.4% vs. 27.6%; p = 0.001). Additional analyses suggest obesity and delay in treatment cadence were factors associated with any improvement of PROMIS-29 domains after regimen completion. Conclusions Race and active cancer treatment were notable barriers to completing a recommended acutherapy regimen. Although effective in managing cancer-related symptoms, non-white patients faced greater impairment in physical functioning, social participation, and pain interference. Future efforts to address these disparities and ensure appropriate schedule adherence can maximize the benefit of acutherapy among cancer patients.

Publisher

Springer Science and Business Media LLC

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3