High caffeine intake as a risk factor for tooth loss: A Study of the National Health and Nutrition Examination Survey (NHANES) 2017-2020

Abstract

Abstract Introduction: Tooth loss can have a wide range of adverse consequences on patients. Caffeine is the main active ingredient in the world's most popular beverages. This study aims to explore any possible connection between the two. Methods: This study analyzed data from the NHANES collected from 2017 to March 2020. Multivariate logistic regression models to examine the association between the caffeine intake and tooth loss. Odds ratios (OR) with 95% confidence intervals (95%CI) was used to evaluate the significance of association. Results: A total of 5,450 participants were finally included in the trial. Adjusted Multivariate logistic regression result showed that tooth loss was strongly linked with higher levels of caffeine intake (OR=1.74; 95% CI 1.40-2.17; p<0.001). Stratified logistic regression analysis showed that only in the subgroups of age (p=0.01) and PIR (p=0.02), the results showed statistical difference. Caffeine intake does not influence tooth loss in ≥ 60 group (p<0.05). Conclusion: In conclusion, increased caffeine consumption may be a factor in tooth loss.