Objective evaluation of skin stiffness in breast cancer-related lymphedema using MyotoPRO

Author:

Mitsuoka Hiroki1,Arima Takahiro1,Ito Yukie1,Fujii Kimihito1,Otsuka Shun1,Shan Xiyao1,Shima Miki2,Takagi Kensuke2,Osawa Mitsuharu2,Naito Munekazu1,Nakano Shogo1,Kodama Akio1

Affiliation:

1. Aichi Medical University

2. Aichi Medical University Hospital

Abstract

Abstract

Purpose Severe lymphedema leads to a decline in quality of life. Skin stiffness is one of the symptoms of lymphedema; however, no objective method has been established to evaluate this symptom. We aimed to examine whether MyotonPRO, which is used to evaluate muscle and fascia stiffness, could evaluate skin stiffness in upper limb lymphedema. Methods Female patients with breast cancer-related lymphedema (BCRL) after unilateral breast cancer surgery were included. Stiffness by MyotonPRO and circumference were measured on both sides 5 and 10 cm from the elbow joint of the forearm and upper arm, respectively. Measurements were compared between the normal and lymphedema limbs. History of breast cancer, lymphedema and comorbidities were collected from medical records, and the relationship with skin stiffness was evaluated. Results The skin stiffness values of normal and lymphedema limbs were 249 ± 50 and 283 ± 56 N/m (p < 0.001) in the upper arm and 306 ± 44 and 353 ± 64 N/m (p < 0.001) in the forearm, respectively, and were significantly greater in the lymphedema limb. The circumferences of the normal and lymphedema limbs were 27.5 ± 3.6 and 29.1 ± 4.0 cm (p < 0.001) for the upper arm and 23.7 ± 2.4 and 25.1 ± 2.9 cm (p < 0.001) for the forearm, respectively, in which the lymphedema limb was significantly larger. In the multiple regression analysis, diabetes had the greatest effect on the lymphedema limb stiffness. Conclusion MyotonPRO can objectively assess chronic skin stiffness in BCRL.

Publisher

Research Square Platform LLC

Reference36 articles.

1. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries;Sung H;CA Cancer J Clin,2021

2. Incidence of unilateral arm lymphoedema after breast cancer: A systematic review and meta-analysis;DiSipio T;Lancet Oncol,2013

3. Burden of lymphedema in long-term breast cancer survivors by race and age;Ren Yumeng, Kebede MA;Cancer,2022

4. Upper limb function and quality of life in breast cancer related lymphedema: A cross-sectional study;Pinto M;Eur J Phys Rehabil Med,2013

5. Psychosocial issues associated with breast cancer-related lymphedema: A literature review;Eaton LH;Curr Breast Cancer Rep,2020

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