Affiliation:
1. E-Da Hospital, I-Shou University
2. E-Da Cancer Hospital, I-Shou university
3. E-Da Hospital, E-Da Cancer Hospital, I-Shou University
Abstract
Abstract
Background
Xanthomas are commonly found in the soft tissues of hyperlipidemic patients. Rarely, they may involve the skeletal system, with various radiographic appearances, mimicking bone malignancies.
Case presentation:
A 55-year-old woman presented with back pain and bilateral lower limb weakness for several months. After serial imaging studies, multifocal osteolytic lesions were identified in the pelvis and spine, with the largest measuring 94 mm in diameter. An abnormal lipid profile and typical cutaneous presentation aided in the final pathological diagnosis of bone xanthoma.
Conclusions
Xanthoma of the bone may be confused with aggressive bone lesions radiologically. Clinical, laboratory, and physical findings, in addition to pathological features, are required to make an accurate diagnosis.
Publisher
Research Square Platform LLC
Reference14 articles.
1. Xanthoma of bone;Bertoni F;Am J Clin Pathol,1988
2. Alhaneedi G, AbuHejleh MS. H. Xanthoma of bone: a mini review.Archieves Surg Oncol. 2018;4.
3. Primary non-hyperlipidemia xanthoma of bone: a case report with review of the literature;Wang Z;Int J Clin Exp Med,2014
4. Familial chylomicronemia syndrome: an under-recognized cause of severe hypertriglyceridaemia;Baass A;J Intern Med,2020
5. A physician’s guide to hyperlipidemia;Fredrickson DS;Mod Concepts Cardiovasc Dis,1972