Molecular identification and validation of four stable QTL for slow-mildewing resistance in Chinese wheat cultivar Bainong 64

Author:

Xu Xiaowan1,Sun Daojie1,Ni Zhongqiu2,Zou Xinyu2,Xu Xiaoting2,Sun Mengjing2,Cao Qiang1,Tong Jingyang2,Ding Fugong2,Zhang Yelun3,Wang Fengju2,Dong Yachao2,Zhang Luyan2,Wang Jiankang2,Xia Xianchun2,He Zhonghu2,Hao Yuanfeng4ORCID

Affiliation:

1. Northwest A&F University College of Agronomy

2. CAAS ICS: Chinese Academy of Agricultural Sciences Institute of Crop Sciences

3. Hebei Academy of Agriculture and Forestry Sciences

4. Chinese Academy of Agricultural Sciences

Abstract

Abstract Wheat powdery mildew, caused by Blumeria graminis f. sp tritici (Bgt), is a devastating fungal disease. Seedlings of Chinese winter wheat cultivar Bainong 64 are susceptible to Bgt but adult plants have maintained slow-mildewing resistance since it was released in 1996. A population of 171 recombinant inbred lines (RILs) developed from cross Jingshuang 16/Bainong 64 (JS16/BN64) was used to dissect genetic components of powdery mildew resistance. A genetic map comprising 5,383 polymorphic markers was constructed using the 15K SNP chip and kompetitive allele-specific PCR (KASP) markers. Composite interval mapping identified four stable QTL on chromosome arms 1DL, 2BS, 2DL, and 6BL in all five environments and their favorable alleles were inherited from BN64. The QTL accounted for 8.3%, 13.8%, 14.4%, and 9.0% of the total phenotypic variances in maximum, respectively. QPmjbr.caas-1DL,situated about 22 Mb from centromere, is probably a new QTL. QPmjbr.caas-2DL located near the end of arm 2DL. Using genetic maps populated with KASP markers, QPmjbr.caas-2BS and QPmjbr.caas-6BL were fine mapped to a 1.8 cM genetic intervals spanning 13.6 Mb (76.0–89.6 Mb) and 1.7 cM and 4.9 Mb (659.9–664.8 Mb), respectively. The four QTL were all independent of stripe rust and leaf rust resistance and were validated for slow-mildewing in another RIL population related to BN64 and a cultivar panel using representative KASP markers spanning each QTL. Since BN64 has been a leading cultivar and an important breeding parent, the QTL and markers reported in this study will be useful for marker-assisted selection of slow-mildewing resistance.

Publisher

Research Square Platform LLC

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