Affiliation:
1. Shiraz University of Medical Sciences
Abstract
Abstract
Background
The present study aims to assess salivary levels of vitamins A, B12, C, D3 and E and compare them with a healthy group.
Methods
58 individuals, attending Shiraz Dental School, Iran, were enrolled in this cross-sectional study (28 OLP patients and 30 healthy controls, age and sex matched.) saliva samples were collected and levels of A, B12, C, D3 and E vitamins were measured. HPLC was used for measuring vitamins A, B12 and E and ELISA kits for vitamins C and D.
Results
Our study population’s mean age was 44.964 ± 10.32, including 67% female. Levels of vitamins A, C, D3 and E were lower in the saliva of OLP patients (P = 0.000, 0.000, 0.013 and 0.000 respectively), but that wasn’t the case for vitamin B12 (P = 0.699). Vitamins A, C and E were interrelated to the erosive type of OLP (P = 0.003, 0.000 and 0.000 respectively). OLP occurrence was significantly correlated with the female population, but not with the age of participants.
Conclusion
Salivary levels of vitamins A, C, D3 and E were significantly lower in OLP patients. There was no statistical difference in vitamin B12 levels in the saliva of OLP patients and the healthy control population.
Publisher
Research Square Platform LLC
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