Effect of biosynthesised nano zinc on blood biochemical profile, antioxidant status and immune response in Vanaraja chicken

Abstract

Abstract Biosynthesized nano zinc as replacement for traditional zinc salt in feed using Vanaraja chicken was evaluated for the response in terms of blood biochemical profile, antioxidant status and immune response. Day-old chicks (n = 324), of a slow growing Vanaraja breed, were randomly assigned to one of the six dietary treatments, each consisting of 54 birds with 9 replicates. The groups were offered basal diet without any supplemental zinc (negative control), basal diet supplemented with 60 mg Zn/kg diet from zinc oxide and the remaining four groups were fed with biosynthesised nano zinc at 15, 30, 45 and 60 mg Zinc per kg diet. The trial lasted for 56 days. The results indicated that, causes significant (P < 0.05) improvement in humoral immunity as compared to control group. Nano zinc at 30 mg/kg diet is sufficient to replace conventional zinc at 60 mg/kg diet. Absence of any significant changes in the serum enzyme profile and biochemical parameters indicated that nano zinc is safe to feed. From the current study, it may be concluded that the conventional zinc oxide can be replaced with nanoparticle forms at a reduced level without any adverse effect on health assessed through serum biochemical profile. In order to recommend the level of dose reduction, more studies with different breeds, indifferent agro-climatic zones during different seasons are recommended.