Affiliation:
1. University El bosque
2. Hospital Pablo Tobon Uribe
Abstract
Abstract
Background
Multifocal neuroendocrine tumors of the lung are rare, usually having low nodal involvement in early stages. We bring to the literature a case of a typical multifocal carcinoid associated to tumors with intrapulmonary lymph node (IPLN) involvement.
Case presentation:
59-year-old female asymptomatic patient with multiple nodules in the right lower lobe, PET-CT with hypermetabolic nodule, adequate pulmonary function, for which a right lower lobectomy was performed plus intrapulmonary lymph nodes dissection in the fresh surgical specimen. The lymph nodes of stations 11, 12, 13 and 14 were sent to pathology. The pathology laboratory report showed that stations 10, 11, 12 and 13 were negative, but station 14 was positive. Thus, changing the stage from Ia2 to IIb.
Conclusion
This patient had an upstaging because of IPLN were positive for metastasis. The search for a more accurate oncologic staging through intrapulmonary lymph node may allow a more accurate staging and therefore a better treatment for the patient regardless type histology.
Publisher
Research Square Platform LLC
Reference7 articles.
1. Trends in the incidence, prevalence, and survival outcomes in patients with neuroendocrine tumors in the United States;Dasari A;JAMA Oncol,2017
2. Relevance of lymph node micrometastases in radically resected endobronchial carcinoid tumors;Mineo TC;Annals of Thoracic Surgery,2005
3. Zhang DG, Chen XC, Zhu D, Qin C, Dong J, Qiu X, et al. Intrapulmonary lymph node metastasis is common in clinically staged IA adenocarcinoma of the lung. Thorac Cancer. 2019 Feb 1;10(2):123–7.
4. Incomplete intrapulmonary lymph node retrieval after routine pathologic examination of resected lung cancer;Ramirez RA;Journal of Clinical Oncology,2012
5. The impact of a novel lung gross dissection protocol on intrapulmonary lymph node retrieval from lung cancer resection specimens;Osarogiagbon RU;Ann Diagn Pathol,2014