Risk factors associated to Streptococcus suis cases in swine farms in Spain

Author:

Neila-Ibáñez Carlos1,Napp Sebastián1,Pailler-García Lola1,Franco-Martínez Lorena2,Cerón José Joaquín2,Aragon Virginia1,Casal Jordi3

Affiliation:

1. Institut de Recerca i Tecnologia Agroalimentàries. Programa de Sanitat Animal. Centre de Recerca en Sanitat Animal (CReSA). Campus de la Universitat Autònoma de Barcelona

2. Interlab-UMU, University of Murcia

3. Universitat Autònoma de Barcelona

Abstract

Abstract Background: Streptococcus suis, an early colonizer of the upper respiratory tract, can cause the S. suis-associated disease, a major infection characterized by meningitis, polyarthritis, and acute death, in piglets mainly around weaning age. However, little is known about the factors responsible for triggering the disease. Therefore, a longitudinal study was carried out, in which a total of six batches from two Spanish swine farms with S. suis problems were repeatedly examined, once in the farrowing unit and twice in the weaning unit. Results: Potential risk factors evaluated included: a) concomitant pathogens such as porcine reproductive respiratory syndrome virus (PRRSV), porcine circovirus type 2, swine influenza virus, and Glaesserella parasuis; b) biomarkers associated to stress (cortisol), inflammation (haptoglobin), and oxidative status (hydrogen peroxide); c) farm environmental factors such as temperature, relative humidity, CO2, and temperature-humidity index; and d) parity and S. suis presence in sows. Three models were built to study the effect of these variables, including two to assess the risk factors involved in the subsequent development of the disease. Presence of S. suis problems during the study was confirmed by its isolation in lesions in both farms. Risk factors for S. suis disease included PRRSV coinfection at weaning (Odds ratio (OR) = 6.69), sow parity (OR = 0.71), haptoglobin before weaning (OR = 1.01), and relative humidity in the farrowing unit as well as temperature at weaning (OR = 1.11 and 0.13, respectively). Conclusions: This study confirms the multifactorial nature of S. suis-associated disease, for which both environmental factors and factors related to the host seem to be involved in the development of the disease.

Publisher

Research Square Platform LLC

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3