Probiotics and Diet Modifications: A Holistic Approach to Tackling Helicobacter pylori with the Help of the Gut Microbiota

Abstract

Abstract Background Helicobacter pylori is a common gastrointestinal bacterium that can cause a range of diseases, including gastritis, peptic ulcer disease, and gastric cancer. The gut microbiota plays an important role in H. pylori colonization and associated diseases. Main body: Lifestyle factors, such as diet, stress, smoking, and alcohol consumption, can impact the gut microbiota composition and function, and may influence the risk of H. pylori colonization and H. pylori-associated diseases. Strategies to promote gut health, such as a healthy diet, stress reduction, smoking cessation, alcohol moderation, regular exercise, adequate sleep, antibiotic stewardship, and probiotic supplementation, may help to reduce the risk of H. pylori colonization and enhance the effectiveness of H. pylori eradication therapy. Furthermore, the gut microbiota may also be a potential target for H. pylori eradication, and personalized treatment approaches based on individual patient characteristics may be necessary to optimize H. pylori eradication rates and reduce the risk of adverse effects. Conclusion Further research is needed to better understand the role of the gut microbiota in H. pylori eradication and to develop more effective treatment strategies. By promoting gut health and developing personalized treatment approaches, we may be able to reduce the burden of H. pylori-associated diseases and improve patient outcomes.