Synthesis of ZnO nanoparticles using Mussaenda frondose and its Applications in Sensor with Antibacterial Studies

Abstract

This work reports the synthesis of as-prepared nanostructured Zinc oxide (ZnO) using Mussaenda frondose leaf extract. The synthesized ZnO nanoparticles (ZnO NPs) were examined using UV-Visible spectrophotometry (UV-VIS), X-ray diffractometry (XRD), Field emission scanning electron microscopy (SEM), Energy dispersive X-ray spectroscopy (EDX), Fourier-transform infrared spectroscopy (FTIR) and Transmission electron microscopy illustrating its Hexagonal Wurtzite structure. Electrochemical behaviour of the dopamine was studied using modified ZnO NPs/CPE. These studies revealed high sensitivity and selectivity for the dopamine(DA) detection in presence of 0.2M phosphate buffer solution of pH 7.4. Antibacterial studies revealed activity against the test pathogens evaluated namely Klebsiella sp. (Gram negative) and S. aureus (Gram positive) by assessing the zone of inhibition in mms following the agar cup diffusion assay.