The association between weight-adjusted waist index and psoriasis in adults: results from NHANES 2009-2014

Abstract

Abstract Background Evidence has indicated that the correlation between obesity and psoriasis is likely multifactorial in nature.Previously, no reports have been made regarding the correlation between weight-adjusted waist index (WWI) and psoriasis. Methods In this cross-sectional research, we examined a cohort of adult participants who provided comprehensive data related to WWI and psoriasis, gathered during the 2009–2014 National Health and Nutrition Examination Survey (NHANES). The calculation for WWI involved dividing waist circumference (WC) by the square root of body weight. We explored the association between WWI and psoriasis through multivariate linear regression modeling and subgroup analyses. The smoothing curve fitting was also applied . Results The study included 15,920 participants aged over 19 years, of whom 438 had a history of psoriasis.It revealed a notable positive correlation between WWI and psoriasis(OR = 1.226; 95% CI, 1.071–1.404, P < 0.05).The quartile with the highest WWI value (OR = 1.551; 95% CI, 1.127–2.135, P < 0.05) had a significantly increased risk of developing psoriasis by 55.1% compared with the quartile with the lowest WWI value. A positive nonlinear connection between WWI and psoriasis was observed in the smoothed curve fitting results. Conclusion Among U.S. adults, levels of WWI are positively associated with increased odds of developing psoriasis.We propose that adopting obesity management strategies based on the WWI could be beneficial in lowering the risk of psoriasis.