Comparison of Brain MRI Findings between Patients with Alzheimer's Disease and Non-Dementia Psychiatric Disorders in the Elderly

Abstract

Abstract Objectives: This study aimed to investigate differences in brain structure between Alzheimer's disease (AD) and non-dementia psychiatric disorders (SNDMD) patients using MRI imaging for accurate diagnosis. Methods: A total of 50 AD patients and 50 SNDMD patients underwent head MRI scans, and brain structures were measured and compared using SPSS software. The MRI results were interpreted by two radiologists. Results: AD patients had wider sulci and larger ventricular systems compared to SNDMD patients and normal elderly individuals. SNDMD patients had less cortical atrophy than AD patients. Conclusion: The findings suggest that MRI is a useful tool for differentiating AD from SNDMD and aiding in early diagnosis. However, it should be noted that MRI is not a definitive diagnostic tool.