In Vivo, Exploring the Antidiabetic and Antimicrobial Effects of Okra Extract in Streptozotocin-Induced Hyperglycemic Conditions

Author:

Alnasser Sulaiman Mohammed1,Almutairy Ali F.1,Ahammed Shakkeela Yusuf Erattil1,Meshal Alotaibi,AlMutairi Khaled M.1,Alhussain Faisal Abdulaziz1,Alharbi Mohammed Askar1,Khan Mohd Masih Uzzaman1

Affiliation:

1. Qassim University

Abstract

Abstract

This paper presents a comprehensive analysis of the phytochemical composition, quality parameters followed by antimicrobial and antidiabetic activity of Abelmoschus esculentus (okra) plant material. The study involved macroscopic examination of the plant material for visual characteristics, and phytochemical screening for various chemical constituents. The presence of flavonoids, amino acids, saponins, tannins, terpenoids, reducing sugars, triterpenes, and lipids was detected, while glycosides, phlobatannins, and cardiac glycosides were absent. The foreign matter content was determined to be 0.17 gm on average. Ash value analysis revealed a mean total ash value of 1.21%, acid insoluble ash of 0.07%, and water-soluble ash of 0.98%. The pH of the plant extract was measured, and the moisture content was determined to be 6.3%. Additionally, the swelling index and foaming index were calculated as quality parameters. Notably, the antimicrobial activity of the okra plant extract showed no significant inhibition zones against various bacterial and fungal strains. The antidiabetic activity of Okra extract was evaluated in streptozotocin-induced diabetes in male albino Wistar rats. Blood glucose level, plasma insulin level and HbA1c% were checked in diabetic and treated groups. After day 21 of the treatment with Okra extract, there was a significant decrease in blood glucose level and plasma insulin level whereas increase in plasma insulin level was observed compared to diabetic group. The results indicated antidiabetic potential of Okra extract. However, further studies are required to elucidate the underlying mechanism of action and long-term effects of okra extract on glycaemic control.

Publisher

Springer Science and Business Media LLC

Reference55 articles.

1. Antibacterial activity and phytochemical screening of some medicinal plants commonly used in Saudi Arabia against selected pathogenic microorganisms;Al-Daihan S;J King Saud Univ Sci,2013

2. Efficacy of Aqueous and Methanol Extracts of Some Medicinal Plants for Potential Antibacterial Activity;PAREKH JJD and CS;Turkish J Biology,2005

3. Standardization strategies for herbal drugs-an overview;Ekka Neeli Rose NKPSPK;Res J Pharm Technol,2008

4. A renaissance in herbal medicine identification: From morphology to DNA;Chen S;Biotechnol Adv,2014

5. Rhamnolipid production by Pseudomonas aeruginosa LBI growing on soapstock as the sole carbon source;Benincasa M;J Food Eng,2002

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3