Synthesis of silica aerogels by sol-gel method and its use as pharmaceutical carriers

Abstract

Abstract Today, researchers are looking for non-toxic matrices that provide preferential release, or specifically controlled release, by loading drugs in these areas. For this reason, areas such as high specific surface silica aerogels are considered, which can increase the absorption by up to 5 times and as a result, one-fifth of the usual amount of drugs can be used as a drug dose. In this research, it was tried to obtain the most desirable method of silica aerogel production with the most available and economical process by examining the sol-gel method. The results of the scanning electron microscope confirmed the production of silica aerogel with nano porosities. X-ray results showed that the produced silica aerogel had an amorphous or amorphous structure and did not have a crystalline structure. In addition, to replace anti-inflammatory which improved the solubility of drugs in the body. As a result, during this study, silica aerogel was produced by sol-gel method with nano porous porosity, and after loading in the pharmaceutical field, the structural and morphological properties were changed in the drugs that could improve the solubility process.