Ocular Refractive Development of Children and Adolescents in the Potential Postpone/Cease Myopic Shift during Early Emmetropization- A Predictive Model Description

Abstract

Abstract Purpose︰To assess the potential for delaying or halting myopic excursion during early emmetropization in children and adolescents. Methods：We followed a population in southern Taiwan, of which we analyzed 69 individuals with refractive errors, a total of 137 eyes, initially between recalled the ages of 7 and 18 years, and recorded for up to 10 years with five refractive corrections at least . We also build a mathematical model to fit/analyze all the data and understand the progression of human eye refractive development as well as the myopic refraction shift during early emmetropization. Results︰The model predictive errors for the fifth refraction were 0.44 dioptres, and the sharpest myopic progression was observed between the ages of 10.21 and 15.93. The average annual refraction change of the eyes was -0.61 dioptres. The myopic refraction of females tended to progress faster than those of males, however the refraction stabilized earlier in early adulthood for females, while it continued to see myopic progression in the males. The individuals had myopia onset earlier than 9, between 9 and 11, and older than 11, also showed different negative growth factor in the model. Conclusions︰The concepts of myopia prevention need to be reformed, that is, instead of regarding hyperopia as reserve at early emmetropization, as paying attention at NG and the time point for an appropriate intervention, so a good model is required.