Abstract
Objective To analyze the clinical features of Mycoplasma pneumoniae pneumonia in children with atopic constitution and non-atopic constitution, and to provide a plan for the treatment of children with atopic constitution.
Methods A total of 446 children hospitalized with Mycoplasma pneumoniae pneumonia in our hospital from June 2023 to December 2023 were selected. They were divided into an atopic group of 156 cases and a non atopic group of 290 cases based on their atopic constitution. The clinical data and laboratory indicators such as white blood cell count (WBC), lymphocyte percentage, neutrophil percentage, eosinophilic percentage, C-reactive protein (CRP), D-dimer, lactate dehydrogenase (LDH), immunoglobulin G (IgG), immunoglobulin M (IgM), immunoglobulin A (IgA), immunoglobulin E (IgE) and chest CT were compared between the two groups.
Results Children in the atopic group were more prone to wheezing and had a longer duration. The eosinophile count, lactate dehydrogenase and IgE levels were higher than those in non atopic group (P<0.05).The proportion of bronchiolitis and severe pneumonia was higher in the atopic group(P<0.05). However, there was no significant difference in the proportion of hormones, bronchoscopy and immunoglobulin used between the two groups.
Conclusion Atopic constitution may be one of the risk factors for severe Mycoplasma pneumoniae pneumonia and bronchiolitis-based Mycoplasma pneumoniae pneumonia. Attention should be paid to the treatment and prognosis of these children.