Copper-catalyzed Intermolecular Regio- and Enantioselective Hy-drosilylation of Alkenes with Prochiral Silanes-Reference-Cited by-同舟云学术

Copper-catalyzed Intermolecular Regio- and Enantioselective Hy-drosilylation of Alkenes with Prochiral Silanes

Published:2024-07-30 Issue: Volume: Page:
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Author:

Xu Yun-He¹^ORCID,Zhu Xiao-Yan¹,Gao Wenyu²,Xu Jian-Lin¹,Wang Zi-Lu¹,Zhao Jinbo²

Affiliation:

1. University of Science and Technology of China

2. Changchun University of Technology

Abstract

This study presents a copper-catalyzed, substrate-controlled regio- and enantioselective intermolecular hydrosilylation method capable of accommodating a broad scope of alkenes and prochiral silanes. The approach offers an efficient and versatile pathway to generate enantioenriched linear and branched alkyl-substituted Si-stereogenic silanes. Key features of this reaction include mild reaction conditions, simple catalytic systems, compatibility with diverse substrates, high yields, and enantioselectivities.

Publisher

Springer Science and Business Media LLC

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