Affiliation:
1. Health Department State University of Santa Cruz - Ilhéus – Bahia – Brazil.
2. Escola Bahiana de Medicina e Saúde Pública – Salvador – Bahia – Brazil.
3. Family Health Program - Barra do Pojuca - Bahia - Brazil.
4. Medical School - Universidade Federal da Bahia – Salvador – Bahia – Brazil.
5. LIDI Laboratório – Itabuna – Bahia – Brazil.
Abstract
Abstract
Introduction
Studies have shown that elevations of the triglyceride/glucose index (TyG) as well as the glycation of hemoglobin index (HGI) are associated with several complications related to insulin resistance (IR).
Objective
To evaluate the association between HGI and TyG index in a sample of non-diabetic individuals and it’s relation with IR.
Method
A cross-sectional study was conducted with 32 non-diabetic individuals. The variables analyzed included age, gender, body mass index, and laboratory data (triglycerides, glucose, HbA1c, and insulin). We calculated the TyG index, HOMA-IR, and HGI. Simple and multivariate linear regression analyses were also performed, in addition to ANOVA and Pearson's correlation between variables.
Results
The multivariate linear regression analysis of the analyzed sample revealed a significant correlation between the TyG index and HGI, which was confirmed by the T-test. The results indicated a strong positive correlation between the TyG index and HGI, with a Pearson correlation coefficient of 0.98.
Conclusion
The HGI, TyG index and IR showed a significant association in the analyzed sample. This suggests that both indices are highly reliable in measuring IR and glucose metabolism and may be markers of risk independent of FPG, and the other variables evaluated in this study.
Publisher
Research Square Platform LLC
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