Affiliation:
1. Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
2. The Fifth Affiliated Hospital of Sun Yat-Sen University
Abstract
Abstract
Background: Several studies have found that the prognostic nutritional index (PNI), controlling nutritional status (CONUT), and Glasgow Prognostic Scores (GPS) of patients with laryngeal cancer accurately predicts their prognosis. However, there is no consensus on the best assessment tool. Therefore, the purpose of this study was to confirm the predictive value of the three nutritional scoring systems for the prognosis of patients with laryngeal cancer.
Methods: In this study, a cohort of 427 patients with laryngeal cancer visiting our hospital was analyzed respectively.PNI, CONUT, and GPS were calculated, and the relationship between these indicators and prognosis was examined.
Results: The optimal cut-off levels for overall survival (OS) of laryngeal cancer patients determined by PNI, CONUT, and GPS were 45, 3, and 0, respectively. When patients were stratified based on these thresholds, OS and disease-free survival (DFS) were significantly decreased in the malnutrition group (all three p<0.05).Laryngeal cancer patients' OS rates were significantly affected by the three scores, according to multivariate analysis.
Conclusions: The three scoring methods had a high predictive value for the prognosis of patients with laryngeal cancer, with GPS having the strongest correlation with the prognosis of laryngeal cancer patients.
Publisher
Research Square Platform LLC