Efficacy of ultrasound-guided percutaneous catheter drainage in severe acute pancreatitis and selection of application timing

Abstract

Abstract Background: Percutaneous catheter drainage (PCD) has been widely used in the treatment of severe acute pancreatitis (SAP), but there is still no consensus on when to perform PCD. This study evaluated the clinical efficacy of PCD in the treatment of SAP with acute accumulation and assessed the impact of the choice of PCD timing on the outcome and complications of patients with SAP. Methods: A total of 99 patients diagnosed with SAP accompanied with acute accumulation from 2017.04 to 2022.04 in the First Affiliated Hospital of Soochow University were included and divided into PCD group (50 cases) and conservative treatment group (49 cases) according to whether they received PCD treatment. The basic information, length of hospital stay, recovery time of laboratory indicators, occurrence of complications, and clinical outcomes were compared between the two groups. The PCD group was further divided into the early PCD group (<2 weeks, 37 cases) and the late PCD group (>2 weeks, 13 cases) according to the time of PCD, and the information mentioned above of the two groups were compared. Results: Compared with the conservative treatment group, the PCD group had significantly shorter recovery time of blood amylase, duration of systemic inflammatory response syndrome (SIRS) (P<0.05), significantly lower incidence rates of complications and mortality (P<0.05). The early PCD group had significantly shorter length of hospital stay and significantly lower incidence of complications than the late PCD group (P < 0.05). Conclusion: PCD is safe and effective in the treatment of SAP and can improve the prognosis of patients. Early PCD is more likely to shorten patients' hospital stay and reduce complications.