Development of Pseudosacral Cyst Following Surgery for Primary Presacral Neuroendocrine Tumors with Liver Metastasis: A Case Report

Abstract

Abstract Introduction: Presacral neuroendocrine tumors (PSNET) are a rare disease that currently lacks a standardized treatment approach. In this report, we present a unique case of PSNET with liver metastasis that progressed into a pseudosacral cyst following complete surgical resection and Sulfatinib treatment with radiofrequency ablation. case summary: A 49-year-old woman presented to our department with hematochezia. Magnetic resonance imaging revealed a presacral mass with liver metastasis. We performed a complete resection of the mass through a transperineal approach and a terminal ileostomy. Postoperative pathology confirmed a G2 neuroendocrine tumor. After multidisciplinary consultation, the patient received targeted treatment with Sulfatinib and underwent radiofrequency ablation of the liver tumors using fluorescence laparoscopy. Six months later, the patient developed an anterior sacral pseudocyst, which required surgical intervention. Conclusion: Before undergoing surgical treatment for presacral neuroendocrinology, it is important to consider the potential risks of poor healing of the presacral incision and formation of pseudocysts. These complications may be caused by various factors, including the procedure itself and the use of targeted drugs.