Abstract
Objective: Effects of sevoflurane and propofol anesthesia on cardioprotective and postoperative recovery were compared in patients with off-pump coronary bypass surgery.
Methods: Preoperative and postoperative myocardial enzymes, other blood
biochemical indexes and clinical outcome were retrospectively analyzed.
Results: Compared with the propofol group, the serum concentration of troponin I (1.19 ± 2.68 ng/mL vs 0.24 ± 0.52 ng/mL, p=0.018) and the brain natriuretic peptide (713.19 ± 849.31 pg/dL vs 403.78 ± 237.23 pg/dL, p=0.017) were significantly lower in sevoflurane group, the postoperative clinical outcome was not significantly different between the two groups.
Conclusion: Sevoflurane was used for anesthesia maintenance could reduce the serum level of cTnI and BNP after off-pump coronary bypass surgery, but the values of clinical outcome were limited.