Analysis of clinical features, biochemical and inflammatory indexes in patients with acute pancreatitis

Author:

Han Minghua1,Jiang Jun2,Huang Lei1

Affiliation:

1. Puren Hospital, Wuhan University of Science and Technology

2. Wuhan University of Science and Technology

Abstract

Abstract Background: Acute pancreatitis (AP) is an inflammatory process unpredictability occurring in the pancreas, imposing a substantial burden on healthcare systems. Herein,Exploring the clinical characteristics of patients with acute pancreatitis, biochemical tests and the role of inflammatory indexes in the disease, to predict the prognosis of acute pancreatitis. Methods: We retrospectively analyzed the clinical data, biochemical and inflammatory indexes of 116 patients with acute pancreatitis diagnosed in Puren Hospital affiliated to Wuhan University of Science and Technology. They were divided into non-severe group and severe group. Counting data were expressed as rate (%), X2 test was used, and measurement data were expressed as mean±standard deviation. Comparison between the two groups was performed by t test, and comparison between the mean of more than two samples was performed by a one-way analysis of variance (ANOVA).P<0.05 was considered to be statistically significant.Receiver operating characteristic curve (ROC) analysis was performed according to the inflammatory indexes of the two groups, and the area under the curve (AUC) and the cut-off value (CUT-OFF) are calculated respectively. Results: The mean age of patients in the severe group was older, and the proportion of underlying diseases was higher. The biochemical and inflammatory indexes in the severe group were higher than those in the non-severe group (P < 0.05). The area under the curve (AUC) and CUT-OFF value (cut-off) were obtained by ROC curve analysis of the inflammatory indexes of white blood cell count (WBC), neutrophil count (NEUT), hypersensitive C-reactive protein (hs-CRP), procalcitonin (PCT) and interleukin-6 (IL-6). Conclusion: Elderly patients with acute pancreatitis accompanied by underlying diseases are more likely to develop into severe disease. In severe patients, biochemical tests are obviously abnormal and inflammatory indexes are increased or even excessive, which is helpful to judge the condition and prognosis of patients with acute pancreatitis.

Publisher

Research Square Platform LLC

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3