Paravascular Vitreous Adhesions in Patients with Myopia Under 30 Years by Swept Source Optical Coherence Tomography

Abstract

Abstract Objectives: To present the characteristics of paravascular vitreous adhesions in patients with myopia under 30 years by SS-OCT. Methods: This was a cross-sectional study. One eye of each subject was enrolled in the study, and the paravascular, macular and optic disc regions were scanned by SS-OCT.The PVA was classified to 4 degrees, Grade 1: No visible separation. Grade2: A slit structure visible, Grade 3: Distinguished separation, but remains to the retina. Grade 4: Complete separation. The degree of macular posterior vitreous detachment (PVD), location of vitreoschisis and presence of granular hyper reflection structure were evaluated and compared within high myopic groups using SPSS. Results: A total of 31 highly myopic eyes and 78 non-highly myopic eyes were enrolled from 5 to 29 years. The varying degrees of PVA in the superior and inferior vascular arch was 29.9% (32), 19.6% (21), 27.1%(29) and 23.4%(25) and 28.6%(30), 17.1%(18), 23.8%(25) and 30.5%(32) separately for 1 to 4 degree of PVA. The degrees of PVA were higher in patients with high myopia than in normal people (P< 0.01). A higher degree of PVA was related to macular PVD and the presence of vitreoschisis (P< 0.05). The granular hyper-reflection structure was mainly in patients without high myopia and was positively related to vitreoschisis (P=0.006, r=0.265). Conclusions: Highly myopic subjects had a higher grade of paravascular vitreous adhesion and the presence of vitreoschisis. The degree of PVA was associated with the macular vitreous adhesion. The granular hyper-reflection structure may play a role in vitreous adhesion.