Synthesis of pyrido-thieno[2,3-d]pyrimidine-7(8H)-carboxylate; Structure identification and X‑ray analyses

Abstract

Abstract Synthesis of oxothiazolidine-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate together with its structure and X‑ray analysis were achieved. The product was obtained during the reaction between diethyl 2-(3-(2-ethoxy-2-oxoethyl)thioureido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate and dimethyl acetylenedicarboxylate. The structure of the obtained compound was confirmed by IR, NMR, mass spectra together with elemental analysis and X-ray structure analysis. The aforementioned compound showed strong intramolecular hydrogen bonds which play important roles in the crystal packing of it.