Affiliation:
1. University of Peshawar
2. University of Swabi
Abstract
Abstract
Grass carp (Ctenopharyngodon idella) was exposed to nanoparticles of different concentrations i.e. copper oxide nanoparticles (CuO-NPs), silver nanoparticles (Ag-NPs) and green synthetic gold nano particles (Au-NPs) each for a period of 14 and 28 days. The DNA damage in the erythrocytes of Grass carp were detected through comet assay technique. The values of Total Comet Score (TCS) were noted for the exposed concentrations with a significant increasing trend (p < 0.05) and ordered as CuO-NPs > Ag-NPs > Au-NPs. The highest TCS value of the exposed erythrocytes was recorded for CuO-NPs at 40 mg L− 1 after 14 days of exposition period. Comparatively, TCS values of erythrocytes exposed to green synthetic Au-NPs at all the concentrations and exposed time was less as compared to the Ag-NPs and CuO-NPs. The study confirmed the adverse effects of nanoparticles on the genetic material of fish cells.
Publisher
Research Square Platform LLC
Reference24 articles.
1. There's plenty of room at the bottom [data storage];Feynman RP;Journal of microelectromechanical systems,1992
2. Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications;Laurent S;Chemical reviews,2008
3. Synthesis and characterization of monodisperse nanocrystals and close-packed nanocrystal assemblies;Murray CB;Annual review of materials science,2000
4. Nanostructures as tailored biological probes;Taton TA;TRENDS in Biotechnology,2002
5. Acute effects of Fe2O3, TiO2, ZnO and CuO nanomaterials on Xenopus laevis;Nations S;Chemosphere,2011