Voltammetric sensor for Tyramine based on poly (L-Aspartic acid) modified Glassy carbon electrode

Abstract

This paper details the use of poly (L-Aspartic acid) modified glassy carbon electrode (p(L-Asp)/GCE) for the sensitive voltammetric determination of tyramine (TYM). The studies reveal that the sensor exhibits high electro catalytic activity towards the electro oxidation of TYM. Under optimum experimental conditions, the determination of TYM has been attained in the range 6.00 × 10^− 6 to 5.00 × 10^− 7 M with a limit of detection 6.55 × 10^− 8 M. At the modified electrode, the electro oxidation was found to be a diffusion controlled process which involves one proton and one electron. The reliability of the proposed method has been verified in physiological fluids.