One-pot, green synthesis of 1H-pyrazolo [1, 2-b] phthalazine-5, 10 diones by ZnFe 2 O 4 nanoparticles an efficient nanocatalyst

Abstract

Abstract Zinc ferrite (ZnFe2O4) nanoparticles were synthesized in the presence of naturally available lemon juice. The synthesized zinc ferrite nanoparticles were characterized by FT-IR, XRD, SEM, EDX, and BET techniques. The zinc ferrite nanoparticles were used for the synthesis of 1H-pyrazolo[1,2-b] phthalazine-5,10-dione derivatives by one-pot coupling reaction of phthalhydrazide, aromatic aldehyde, and malononitrile under conventional reflux condition. This green synthetic approach offers important features like non-toxic substances, maximum yields with a short reaction time, and easy purification of a product. It is a highly efficient, cheap, and reusable nanocatalyst.