Lactational exposure of human infants to metal (loid)s: A comparison of industrial and urban inhabitants in north of the Persian Gulf

Author:

Amiri Leila1,Doroodzani Atefeh Khalili1,Ostovar Afshin2,Dobaradaran Sina1,Mohammadi Azam1,Nabipour Iraj1,Raeisi Alireza3,Malekizadeh Hasan1,Farhadi Akram1,Saeedi Reza4,Afrashteh Sima1,Nazmara Shahrokh2,Keshtkar Mozhgan1

Affiliation:

1. Bushehr University of Medical Sciences

2. Tehran University of Medical Sciences

3. Shiraz University of Medical Sciences

4. Shahid Beheshti University of Medical Sciences

Abstract

Abstract In this study, postnatal metal (loid)s (MLs) exposure was compared between the petrochemical and gas area of Asaluyeh (PGA) and urban area of Kaki (UA) in Bushehr province, Iran. Two hundred human breast milk (BM) samples from the industrial and urban areas were analyzed for MLs using Inductivity Coupled Plasma-Optical Emission Spectrometry (ICP-OES). Boron (B), cooper (Cu), iron (Fe), and nickel (Ni) were found at the highest levels in both study areas. Adjusted multiple linear regression models revealed that the mean concentration of total MLs in BM samples collected from the PGA was statistically significantly greater than that of the UA (655.85 vs. 338.17 µg/L). Also, the mean concentrations of all detected MLs in BM samples collected from the PGA were statistically significantly higher than those collected from the UA. The hazard index (HI) of combined MLs in the PGA and UA illustrated non-cancer risk for infants. Lead (Pb) and chromium (Cr) in the PGA and Cr in the UA showed the risk of cancer. So it can be concluded that nursing infants from an industrial area are most at risk for MLs exposure during entire lactation course than those from an urban area.

Publisher

Research Square Platform LLC

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