Exploring the impact of diabetes on the prognosis of gastric cancer patients based on the survival data of gastric cancer patients in NHANES database and the survival data of Chinese gastric cancer patients-Reference-Cited by-同舟云学术

Exploring the impact of diabetes on the prognosis of gastric cancer patients based on the survival data of gastric cancer patients in NHANES database and the survival data of Chinese gastric cancer patients

Published:2023-10-12 Issue: Volume: Page:
ISSN:
Container-title:
language:
Short-container-title:

Author:

Zhou Weiguo¹,Cheng Yixian¹,Chen Junjie¹,Chen Haosong¹,Wang Mingqing¹,Cao Wei¹,He Cuiqi²,Zhao Qi²,Zhang Peng¹,Wang Wei³,Zheng Yun¹,Chen Bo¹

Affiliation:

1. First Affiliated Hospital of Anhui Medical University

2. Anhui Medical University

3. The Second Affiliated Hospital of Bengbu Medical College

Abstract

Abstract Objectives At present, the prognosis of gastric cancer patients is poor, and many factors affect their prognosis. This study mainly explored the relationship between diabetes and the prognosis of patients with gastric cancer. Methods Collect clinical data of gastric cancer patients from the NHANES database from 1999 to 2020 and the First Affiliated Hospital of Anhui Medical University from 2015 to 2017. Integrating survival time, survival status, and covariates affecting prognosis in gastric cancer patients. To explore the relationship between diabetes and prognosis of gastric cancer patients by univariate and multivariate cox regression analysis Results In the clinical data of gastric cancer patients in NHANES database, in the three models constructed, there were differences between the history of diabetes and the prognosis of gastric cancer patients (p < 0.05). In the clinical data of gastric cancer patients in the first affiliated hospital of anhui medical university, there were differences between diabetes and gastric cancer prognosis in univariate and multivariate cox regression analysis (p < 0.05). Conclusions By analyzing the clinical data of gastric cancer patients in NHANES database and the First Affiliated Hospital of Anhui Medical University, we found that diabetes is a risk prognostic factor for gastric cancer.

Publisher

Research Square Platform LLC

Reference30 articles.

1. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries;Sung H;CA-CANCER J CLIN,2021

2. Burden of Gastric Cancer;Thrift AP;CLIN GASTROENTEROL H,2020

3. Incidence of gastric cancer in the USA during 1999 to 2013: a 50-state analysis;Wang Z;INT J EPIDEMIOL,2018

4. Gastric Cancer Epidemiology;Thrift AP;Gastrointest Endosc Clin N Am,2021

5. SEER. Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) SEER*Stat Database: Incidence - SEER Research Data, 17 Registries, Nov 2021 Sub (2000–2019) – Linked To County Attributes – Time Dependent (1990–2019) Income/Rurality, 1969–2020 Counties, National Cancer Institute, DCCPS, Surveillance Research Program, released April 2022, based on the November 2021 submission (2022).: SEER. Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) SEER*Stat Database: Incidence - SEER Research Data, 17 Registries, Nov 2021 Sub (2000–2019) – Linked To County Attributes – Time Dependent (1990–2019) Income/Rurality, 1969–2020 Counties, National Cancer Institute, DCCPS, Surveillance Research Program, released April 2022, based on the November 2021 submission (2022).