Abstract
Background
Chondroblastoma (CBL) is a rare benign bone tumor with potentially local recurrence and metastases. At present, the local recurrence risk factors are controversial. The purpose of this study is to analysis local recurrence factors in our medical centre. Sharing Our Therapeutic Experience.
Methods
In a retrospective study, we identified 28 patients who were diagnosed pathologically and an analysis that included age at diagnosis, gender, side, tumor location, tumor volume, epiphyseal plate status, affected epiphyseal plate, aneurysmal bone cyst, surgical therapy was performed. Kaplan-Meier estimators were used to analyze the local recurrence-free survival (LRFS). Intraclass Correlation Coefficient (ICC) and Kappa coefficient were utilized for the analysis of inter-rater variability in medical evaluations.
Results
All relapsed patients were over the 11 years old. There was a statistically significant difference in tumor volume between patients with recurrence and those without recurrence, as determined by the unpaired t-test. Furthermore, the Kaplan-Meier curve revealed a statistically significant association between local recurrence-free survival and tumor volume, with a distinct separation observed between patients with tumor volumes greater than 25 cm³ and those with volumes less than 25 cm³.
Conclusion
Curettage, combined with alcohol as an adjuvant and bone grafting, has demonstrated promising outcomes. However, it is noteworthy that a larger tumor size correlates with an increased likelihood of recurrence.