Human Randomized Controlled Trail Clinical and Biochemical Evaluation Oral Irrigator Effectiveness in Patients Under Orthodontic Treatment

Abstract

Abstract Objective The aim of this study is to compare the effectiveness of oral irrigator (OI) with interdental brush (IB) clinically and biochemically in orthodontic patients. Materials and Methods Thirty patients were randomly divided into two equal groups; patients using OI in addition to manuel brushing (OI-group), patients using IB in addition to manual brushing (IB-group). The data was collected in the baseline, 2nd, 4th and 8th weeks. Periodontal indexes were recorded clinically and interleukin (IL)-1β, IL-10, matrix metalloproteinase (MMP)-1, MMP-8 levels in gingival crevicular fluid were evaluated biochemically. Results The gingival index and bleeding on probing values at the 8th week and plaque index values at the 2nd, 4th and 8th weeks were found to be statistically lower in the OI-group compared to IB-group. IL-1β total and concentration values at the 2nd week, MMP-8 total and concentration values at the 4th and 8th weeks were statistically lower in the OI-group compared to IB-group. There were no significant differences in MMP-1 and IL-10 total and concentration values between the groups at any time interval of the study. Conclusions The result of our study showed that usage of oral irrigator in addition to toothbrush appears to be as effective as interdental brush in patients under orthodontic treatment. Clinical Revelance There is limited information about OI’s using in orthodontic patients. The results of this study showed that oral irrigators can be used as an alternative oral care device for the interdental cleaning (NCT05562986).