Affiliation:
1. 1Department of Endocrinological Gynecology, Medical University of Silesia, Katowice
2. 2Chair and Department of Gynecology, Obstetrics and Gynecological Oncology, School of Health Sciences in Katowice, Medical University of Silesia, Katowice
Abstract
Abstract
Acute genital ulcers (AGU) can affect girls and women of all ages. In children, they
often appear as an emergency and remain a diagnostic challenge for pediatricians,
gynecologists, and dermatologists. Prompt diagnosis and identification of disease-
related factors help to implement appropriate treatment. Firstly, it is crucial to properly
compile the medical background of the patient. Infectious, autoimmune, malignant,
traumatic, or vaccines are the possible conditions. Also, new infectious agents, such
as SARS-CoV-2 and vaccinations against it - COVID-19, may play a significant role
in the development of atypical clinical symptoms. We present a case of a 12-years-
old girl with acute genital ulcers and history of autoimmune diseases. She had
periodic fever - aphthous stomatitis - pharyngitis - adenopathy (PFAPA) syndrome
and Henoch-Schönlein purpura in the past. Additionally, she was vaccinated against
SARS-CoV-2 shortly before the lesions appeared. Review of literature is focused on
the possible causal link between appearance of AGU, autoimmunity, and COVID-19
vaccination.
Publisher
Research Square Platform LLC