Affiliation:
1. CHU Grenoble: Centre Hospitalier Universitaire Grenoble Alpes
2. CH-Chambery: Centre Hospitalier Metropole Savoie
Abstract
Abstract
Nocardiosis is a disease that mainly affects immunocompromised patients. Inhaled corticosteroids are standard of care for asthma. This treatment can induce respiratory infections but no case of bronchiolitis nocardiosis have been described so far. A 58-year-old man, with a controlled moderate allergic asthma, started since two years coughing and having dyspnoea during efforts. Within two months, although inhaled corticosteroids were increased to high doses, symptoms worsened linked to a severe obstructive ventilatory disorder as pulmonary function tests (PFT) revealed. Small-scale lesions (< 10%) were found on chest computed tomography (CT). A bronchoalveolar lavage found Nocardia abscessus. After six months of Sulfamethoxazole/Trimethoprim, PFT results improved and chest CT became completely normal. We therefore present the case of a bronchiolitis nocardiosis with several bronchial syndrome and the only immunosuppressive factor found are inhaled corticosteroids (ICS).
Publisher
Research Square Platform LLC
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